No. 1: San Diego Padres
The Padres led the Majors in ERA last season, and there's no reason to believe they can't do it again. The three keys to their rotation -- Jake Peavy, Chris Young and Greg Maddux -- are all back, and though some might expect a decline from Maddux at 42 years of age, the Padres aren't worried. Especially not when Young and Peavy, who combined for 28 wins and a 2.79 ERA last year, seemingly still have room to improve. Don't underestimate the addition of former rookie sensation Mark Prior, either. Though the odds of Prior making an impact remain low, his presence could pay significant dividends down the line.